Finding new drugs requires screening vast numbers of compounds to identify those that interact with a biological target.

Single-molecule techniques have advanced our understanding of DNA–protein interactions, yet simultaneously tracking enzyme position on DNA, determining binding dynamics and resolving enzyme activity ...

Most microscopes can only illuminate objects down to a certain size before tiny features blur together. This blurring is known as the diffraction limit of light. Super-resolution imaging techniques, ...

Thymine modified polymer for delivering DNA into cells. A thymine modified compound, poly (ethylene glycol) (PEG), is bound to DNA through an annealing process, then delivered by intramuscular ...

In recent years, technologies that allow scientists to study a person's DNA at single-molecule resolution have vastly expanded our knowledge of the human genome, the microbiome, and the genetic basis ...

A systematic analysis of hundreds of WGBS datasets finds that apparent mitochondrial DNA methylation is driven mainly by ...

Scientists have discovered how viruses help dead bacteria continue producing DNA, revealing a surprising process that could ...

In his later years, Watson's reputation was tarnished by comments on genetics and race that led him to be ostracized by the ...

DNA is the molecular basis of heredity, the inherited traits that pass between generations in a person's family tree. Embodied in the sequence of base pairs, DNA carries information between ...

An illustration showing a short segment of a single DNA strand being cut out with a gene-editing tool and replaced with a ...

In one sentence: DNA origami is a self-assembly technique that folds a long single-stranded DNA molecule into precisely defined nanoscale shapes using hundreds of short, computer-designed staple ...

Using advanced imaging techniques and precise microfluidics control to stretch out curly DNA into a straight line, new research demonstrates techniques for stretching and immobilizing DNA with minimum ...